Early Efficacy and Pharmacokinetics

Early Efficacy and Pharmacokinetics

In vitro efficacy：In vitro efficacy evaluation is the testing and evaluation of the efficacy of drugs in an in vitro environment, used to preliminarily screen the effectiveness and safety of drugs. Beixin Biotechnology can provide customized in vitro pharmacological testing services, including but not limited to the following testing services:

                                  Display of freshly isolated mouse primary liver cells                                                                  Off target prediction of drugs in vitro

In vivo pharmacological effects and drug metabolism：PK/PD is an important component of the development process of small nucleic acid drugs. It studies the effects and strength of drugs in animal bodies, changes in drug concentration, and dynamic changes in drug absorption, distribution, metabolism, and excretion in the body. It provides a more accurate and comprehensive understanding of the effects of small nucleic acid drugs that vary with dosage and time, thereby providing a more scientific theoretical basis for the safety and effectiveness of clinical medication. Beixin Biotechnology can provide model construction, customized experimental plans, professional PD/PK analysis, and more.

In vitro efficacy maintenance testing of drugs

In vitro ADME service project：In vitro ADME refers to the process of simulating the absorption, distribution, metabolism, and excretion of drugs in the body. It is an important part of drug development, using advanced biotechnology, molecular biology techniques, and engineered tissue tools to simulate the physiological environment and biotransformation process in the human body, in order to evaluate key properties such as drug bioavailability, metabolic stability, and toxicity. Its advantage lies in the ability to predict the ADME properties of drugs in the early stages, saving research and development time and costs. At the same time, it uses human cells and enzyme systems to more accurately predict the behavior of drugs in the human body, reduce research and development risks, avoid ethical issues in animal experiments, and support high-throughput screening to quickly evaluate a large number of compounds, accelerating the drug discovery process. Beixin Biotechnology can provide the following service items: